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Formation of AAV Single Stranded DNA Genome from a Circular Plasmid in Saccharomyces cerevisiae
Adeno-associated virus (AAV)-based vectors are promising tools for targeted transfer in gene therapy studies. Many efforts have been accomplished to improve production and purification methods. We thought to develop a simple eukaryotic system allowing AAV replication which could provide an excellent...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154452/ https://www.ncbi.nlm.nih.gov/pubmed/21853137 http://dx.doi.org/10.1371/journal.pone.0023474 |