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Designing of Highly Effective Complementary and Mismatch siRNAs for Silencing a Gene

In past, numerous methods have been developed for predicting efficacy of short interfering RNA (siRNA). However these methods have been developed for predicting efficacy of fully complementary siRNA against a gene. Best of author's knowledge no method has been developed for predicting efficacy...

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Detalles Bibliográficos
Autores principales: Ahmed, Firoz, Raghava, Gajendra P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154470/
https://www.ncbi.nlm.nih.gov/pubmed/21853133
http://dx.doi.org/10.1371/journal.pone.0023443