Transfection of shRNA-encoding Minivector DNA of a few hundred base pairs to regulate gene expression in lymphoma cells

This work illustrates the utility of Minivector DNA, a non-viral, supercoiled gene therapy vector incorporating short hairpin RNA from an H1 promoter. Minivector DNA is superior to both plasmid DNA and small interfering RNA (siRNA) in that it has improved biostability while maintaining high cell tra...

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Detalles Bibliográficos
Autores principales: Zhao, N, Fogg, J M, Zechiedrich, L, Zu, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Enabling Technologies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154479/
https://www.ncbi.nlm.nih.gov/pubmed/20962872
http://dx.doi.org/10.1038/gt.2010.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154479/
https://www.ncbi.nlm.nih.gov/pubmed/20962872
http://dx.doi.org/10.1038/gt.2010.123

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