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Mechanism(s) of Toxic Action of Zn(2+) and Selenite: A Study on AS-30D Hepatoma Cells and Isolated Mitochondria
Mitochondria of AS-30D rat ascites hepatoma cells are found to be the main target for Zn(2+) and sodium selenite (Na(2)SeO(3)). High [mu]M concentrations of Zn(2+) or selenite were strongly cytotoxic, killing the AS-30D cells by both apoptotic and necrotic ways. Both Zn(2+) and selenite produced str...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154521/ https://www.ncbi.nlm.nih.gov/pubmed/21860797 http://dx.doi.org/10.1155/2011/387297 |