Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities

Ectopic expression of recombinant human bone morphogenetic protein 2 (rhBMP2) induces osteogenesis, while ectopic expression of rhBMP12 and rhBMP13 induces the formation of tendon-like tissue. Despite their different in vivo activities, all three ligands bound to the type I bone morphogenic protein...

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Detalles Bibliográficos
Autores principales: Berasi, Stephen P, Varadarajan, Usha, Archambault, Joanne, Cain, Michael, Souza, Tatyana A, Abouzeid, Abe, Li, Jian, Brown, Christopher T, Dorner, Andrew J, Seeherman, Howard J, Jelinsky, Scott A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: e-Century Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154542/
https://www.ncbi.nlm.nih.gov/pubmed/21702718
http://dx.doi.org/10.3109/08977194.2011.593178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154542/
https://www.ncbi.nlm.nih.gov/pubmed/21702718
http://dx.doi.org/10.3109/08977194.2011.593178

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