Differential Contribution of PB1-F2 to the Virulence of Highly Pathogenic H5N1 Influenza A Virus in Mammalian and Avian Species

Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts. PB1-F2 is an alternative translation product of the viral PB1 segment that was initially characterized as a pro-apoptotic mitocho...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmolke, Mirco, Manicassamy, Balaji, Pena, Lindomar, Sutton, Troy, Hai, Rong, Varga, Zsuzsanna T., Hale, Benjamin G., Steel, John, Pérez, Daniel R., García-Sastre, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154844/
https://www.ncbi.nlm.nih.gov/pubmed/21852950
http://dx.doi.org/10.1371/journal.ppat.1002186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154844/
https://www.ncbi.nlm.nih.gov/pubmed/21852950
http://dx.doi.org/10.1371/journal.ppat.1002186

Ejemplares similares