Cargando…

Role for casein kinase 1 in the phosphorylation of Claspin on critical residues necessary for the activation of Chk1

The mediator protein Claspin is critical for the activation of the checkpoint kinase Chk1 during checkpoint responses to stalled replication forks. This function involves the Chk1-activating domain (CKAD) of Claspin, which undergoes phosphorylation on multiple conserved sites. These phosphorylations...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Zheng, Capalbo, Luisa, Glover, David M., Dunphy, William G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154880/ https://www.ncbi.nlm.nih.gov/pubmed/21680713 http://dx.doi.org/10.1091/mbc.E11-01-0048

Ejemplares similares

Structural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein
por: Day, Matthew, et al.
Publicado: (2021)

Cdc7 activates replication checkpoint by phosphorylating the Chk1-binding domain of Claspin in human cells
por: Yang, Chi-Chun, et al.
Publicado: (2019)

Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling
por: Yan, Shan, et al.
Publicado: (2006)

Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses
por: Hsiao, Hao-Wen, et al.
Publicado: (2023)

HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability
por: Zhu, Min, et al.
Publicado: (2014)

DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response
por: Lin, Yu-Fen, et al.
Publicado: (2014)

TRIM21 suppresses CHK1 activation by preferentially targeting CLASPIN for K63-linked ubiquitination
por: Zhu, Xuefei, et al.
Publicado: (2022)

The HNF-1β―USP28―Claspin pathway upregulates DNA damage-induced Chk1 activation in ovarian clear cell carcinoma
por: Ito, Fuminori, et al.
Publicado: (2018)

Correction: Hsiao et al. Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses. Biomolecules 2023, 13, 125
por: Hsiao, Hao-Wen, et al.
Publicado: (2023)

CK1δ Kinase Activity Is Modulated by Chk1-Mediated Phosphorylation
por: Bischof, Joachim, et al.
Publicado: (2013)

The kinase domain residue serine 173 of Schizosaccharomyces pombe Chk1 kinase is critical for the response to DNA replication stress
por: Coulton, Naomi, et al.
Publicado: (2017)

The Xenopus Chk1 Protein Kinase Mediates a Caffeine-sensitive Pathway of Checkpoint Control in Cell-free Extracts
por: Kumagai, Akiko, et al.
Publicado: (1998)

Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells
por: Yang, Chi-Chun, et al.
Publicado: (2016)

Connexin 43 phosphorylation by casein kinase 1 is essential for the cardioprotection by ischemic preconditioning
por: Hirschhäuser, Christine, et al.
Publicado: (2021)

Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation via derepression of Chk1 catalytic activity
por: Walker, M, et al.
Publicado: (2009)

Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation
por: Yu, Xinfang, et al.
Publicado: (2020)

TopBP1 and Claspin contribute to the radioresistance of lung cancer brain metastases
por: Choi, Seung Ho, et al.
Publicado: (2014)

CHK1 phosphorylates PRIMPOL to promote replication stress tolerance
por: Mehta, Kavi P. M., et al.
Publicado: (2022)

AR phosphorylation and CHK2 kinase activity regulates IR-stabilized AR–CHK2 interaction and prostate cancer survival
por: Ta, Huy Q, et al.
Publicado: (2020)

The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks
por: Lee, Joon, et al.
Publicado: (2013)

γH2AX and Chk1 phosphorylation as predictive pharmacodynamic biomarkers of Chk1 inhibitor-chemotherapy combination treatments
por: Rawlinson, Rebecca, et al.
Publicado: (2014)

Interdependent Phosphorylation within the Kinase Domain T-loop Regulates CHK2 Activity
por: Guo, Xin, et al.
Publicado: (2010)

Chk1, Chk2, is the amplifier on?
por: Dove, Alan W.
Publicado: (2001)

Tubulin phosphorylation by casein kinase II is similar to that found in vivo
Publicado: (1987)

Casein kinase 1 controls the activation threshold of an α-arrestin by multisite phosphorylation of the interdomain hinge
por: Herrador, Antonio, et al.
Publicado: (2015)

Casein kinase 2 regulates telomere protein complex formation through Rap1 phosphorylation
por: Inoue, Haruna, et al.
Publicado: (2019)

Initiation of Drosophila chorion gene amplification requires Claspin and mus101, whereas Claspin, but not mus101, plays a major role during elongation
por: Choi, Seung Ho, et al.
Publicado: (2017)

The Drosophila Splicing Factor PSI Is Phosphorylated by Casein Kinase II and Tousled-Like Kinase
por: Taliaferro, J. Matthew, et al.
Publicado: (2013)

Phosphorylation-Dependent Interactions between Crb2 and Chk1 Are Essential for DNA Damage Checkpoint
por: Qu, Meng, et al.
Publicado: (2012)

Resistance to BET inhibitors in lung adenocarcinoma is mediated by casein kinase phosphorylation of BRD4
por: Calder, Jack, et al.
Publicado: (2021)

Phosphorylation by Casein Kinase 2 Facilitates Psh1 Protein-assisted Degradation of Cse4 Protein
por: Hewawasam, Geetha S., et al.
Publicado: (2014)

Rotavirus NSP1 Requires Casein Kinase II-Mediated Phosphorylation for Hijacking of Cullin-RING Ligases
por: Davis, Kaitlin A., et al.
Publicado: (2017)

Casein kinase 1δ/ε phosphorylates fused in sarcoma (FUS) and ameliorates FUS-mediated neurodegeneration
por: Kishino, Yuya, et al.
Publicado: (2022)

The DNA-Binding Domain of S. pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers
por: Zech, Juergen, et al.
Publicado: (2015)

Molecular dissection of the E6 PBM identifies essential residues regulating Chk1 phosphorylation and subsequent 14-3-3 recognition
por: Vats, Arushi, et al.
Publicado: (2023)

Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis
por: Mikawa, Takumi, et al.
Publicado: (2020)

Casein Kinase 2 Dependent Phosphorylation of Neprilysin Regulates Receptor Tyrosine Kinase Signaling to Akt
por: Siepmann, Martin, et al.
Publicado: (2010)

Rad9, Rad17, TopBP1 and Claspin Play Essential Roles in Heat-Induced Activation of ATR Kinase and Heat Tolerance
por: Tuul, Munkhbold, et al.
Publicado: (2013)

Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential
por: Madgwick, Suzanne, et al.
Publicado: (2022)

Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer’s disease
por: Bettegazzi, Barbara, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_m84lj6rdrpmu7l7pp7860qh2ek