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Single Molecule Analysis of c-myb Alternative Splicing Reveals Novel Classifiers for Precursor B-ALL

The c-Myb transcription factor, a key regulator of proliferation and differentiation in hematopoietic and other cell types, has an N-terminal DNA binding domain and a large C-terminal domain responsible for transcriptional activation, negative regulation and determining target gene specificity. Over...

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Detalles Bibliográficos
Autores principales: Zhou, Ye E., O'Rourke, John P., Edwards, Jeremy S., Ness, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154906/
https://www.ncbi.nlm.nih.gov/pubmed/21853052
http://dx.doi.org/10.1371/journal.pone.0022880