Differential Effects of TNF (TNFSF2) and IFN-γ on Intestinal Epithelial Cell Morphogenesis and Barrier Function in Three-Dimensional Culture

BACKGROUND: The cytokines TNF (TNFSF2) and IFNγ are important mediators of inflammatory bowel diseases and contribute to enhanced intestinal epithelial permeability by stimulating apoptosis and/or disrupting tight junctions. Apoptosis and tight junctions are also important for epithelial tissue morp...

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Detalles Bibliográficos
Autores principales: Juuti-Uusitalo, Kati, Klunder, Leon J., Sjollema, Klaas A., Mackovicova, Katarina, Ohgaki, Ryuichi, Hoekstra, Dick, Dekker, Jan, van IJzendoorn, Sven C. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154921/
https://www.ncbi.nlm.nih.gov/pubmed/21853060
http://dx.doi.org/10.1371/journal.pone.0022967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154921/
https://www.ncbi.nlm.nih.gov/pubmed/21853060
http://dx.doi.org/10.1371/journal.pone.0022967

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