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Strategy to Find Molecular Signatures in a Small Series of Rare Cancers: Validation for Radiation-Induced Breast and Thyroid Tumors

Methods of classification using transcriptome analysis for case-by-case tumor diagnosis could be limited by tumor heterogeneity and masked information in the gene expression profiles, especially as the number of tumors is small. We propose a new strategy, EMts_2PCA, based on: 1) The identification o...

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Detalles Bibliográficos
Autores principales: Ugolin, Nicolas, Ory, Catherine, Lefevre, Emilie, Benhabiles, Nora, Hofman, Paul, Schlumberger, Martin, Chevillard, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154936/
https://www.ncbi.nlm.nih.gov/pubmed/21853153
http://dx.doi.org/10.1371/journal.pone.0023581