An RNA Interference Phenotypic Screen Identifies a Role for FGF Signals in Colon Cancer Progression

In tumor cells, stepwise oncogenic deregulation of signaling cascades induces alterations of cellular morphology and promotes the acquisition of malignant traits. Here, we identified a set of 21 genes, including FGF9, as determinants of tumor cell morphology by an RNA interference phenotypic screen...

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Detalles Bibliográficos
Autores principales: Leushacke, Marc, Spörle, Ralf, Bernemann, Christof, Brouwer-Lehmitz, Antje, Fritzmann, Johannes, Theis, Mirko, Buchholz, Frank, Herrmann, Bernhard G., Morkel, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154943/
https://www.ncbi.nlm.nih.gov/pubmed/21853123
http://dx.doi.org/10.1371/journal.pone.0023381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154943/
https://www.ncbi.nlm.nih.gov/pubmed/21853123
http://dx.doi.org/10.1371/journal.pone.0023381

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