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Variance of Gene Expression Identifies Altered Network Constraints in Neurological Disease

Gene expression analysis has become a ubiquitous tool for studying a wide range of human diseases. In a typical analysis we compare distinct phenotypic groups and attempt to identify genes that are, on average, significantly different between them. Here we describe an innovative approach to the anal...

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Detalles Bibliográficos
Autores principales: Mar, Jessica C., Matigian, Nicholas A., Mackay-Sim, Alan, Mellick, George D., Sue, Carolyn M., Silburn, Peter A., McGrath, John J., Quackenbush, John, Wells, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154954/
https://www.ncbi.nlm.nih.gov/pubmed/21852951
http://dx.doi.org/10.1371/journal.pgen.1002207