Cargando…
Variance of Gene Expression Identifies Altered Network Constraints in Neurological Disease
Gene expression analysis has become a ubiquitous tool for studying a wide range of human diseases. In a typical analysis we compare distinct phenotypic groups and attempt to identify genes that are, on average, significantly different between them. Here we describe an innovative approach to the anal...
Autores principales: | Mar, Jessica C., Matigian, Nicholas A., Mackay-Sim, Alan, Mellick, George D., Sue, Carolyn M., Silburn, Peter A., McGrath, John J., Quackenbush, John, Wells, Christine A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154954/ https://www.ncbi.nlm.nih.gov/pubmed/21852951 http://dx.doi.org/10.1371/journal.pgen.1002207 |
Ejemplares similares
-
A Cross-Study Transcriptional Analysis of Parkinson's Disease
por: Sutherland, Greg T., et al.
Publicado: (2009) -
attract: A Method for Identifying Core Pathways That Define Cellular Phenotypes
por: Mar, Jessica C., et al.
Publicado: (2011) -
Rotenone Susceptibility Phenotype in Olfactory Derived Patient Cells as a Model of Idiopathic Parkinson’s Disease
por: Murtaza, M., et al.
Publicado: (2016) -
NRF2 Activation Restores Disease Related Metabolic Deficiencies in Olfactory Neurosphere-Derived Cells from Patients with Sporadic Parkinson's Disease
por: Cook, Anthony L., et al.
Publicado: (2011) -
Fibroblast and Lymphoblast Gene Expression Profiles in Schizophrenia: Are Non-Neural Cells Informative?
por: Matigian, Nicholas A., et al.
Publicado: (2008)