Suppression of Scant Identifies Endos as a Substrate of Greatwall Kinase and a Negative Regulator of Protein Phosphatase 2A in Mitosis

Protein phosphatase 2A (PP2A) plays a major role in dephosphorylating the targets of the major mitotic kinase Cdk1 at mitotic exit, yet how it is regulated in mitotic progression is poorly understood. Here we show that mutations in either the catalytic or regulatory twins/B55 subunit of PP2A act as...

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Detalles Bibliográficos
Autores principales: Rangone, Hélène, Wegel, Eva, Gatt, Melanie K., Yeung, Eirene, Flowers, Alexander, Debski, Janusz, Dadlez, Michal, Janssens, Veerle, Carpenter, Adelaide T. C., Glover, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154957/
https://www.ncbi.nlm.nih.gov/pubmed/21852956
http://dx.doi.org/10.1371/journal.pgen.1002225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154957/
https://www.ncbi.nlm.nih.gov/pubmed/21852956
http://dx.doi.org/10.1371/journal.pgen.1002225

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