Ku Must Load Directly onto the Chromosome End in Order to Mediate Its Telomeric Functions

The Ku heterodimer associates with the Saccharomyces cerevisiae telomere, where it impacts several aspects of telomere structure and function. Although Ku avidly binds DNA ends via a preformed channel, its ability to associate with telomeres via this mechanism could be challenged by factors known to...

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Detalles Bibliográficos
Autores principales: Lopez, Christopher R., Ribes-Zamora, Albert, Indiviglio, Sandra M., Williams, Christopher L., Haricharan, Svasti, Bertuch, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154960/
https://www.ncbi.nlm.nih.gov/pubmed/21852961
http://dx.doi.org/10.1371/journal.pgen.1002233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154960/
https://www.ncbi.nlm.nih.gov/pubmed/21852961
http://dx.doi.org/10.1371/journal.pgen.1002233

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