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Npp1 promotes atherosclerosis in ApoE knockout mice

Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) generates inorganic pyrophosphate (PP(i)), a physiologic inhibitor of hydroxyapatite deposition. In a previous study, we found NPP1 expression to be inversely correlated with the degree of atherosclerotic plaque calcification. Moreover, func...

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Detalles Bibliográficos
Autores principales: Nitschke, Yvonne, Weissen-Plenz, Gabriele, Terkeltaub, Robert, Rutsch, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154990/
https://www.ncbi.nlm.nih.gov/pubmed/21477221
http://dx.doi.org/10.1111/j.1582-4934.2011.01327.x