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Age-related changes of neuron numbers in the frontal cortex of a transgenic mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder, characterized by amyloid plaque accumulation, intracellular tangles and neuronal loss in selective brain regions. The frontal cortex, important for executive functioning, is one of the regions that are affected. Here, we investigated the neur...

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Detalles Bibliográficos
Autores principales: Lemmens, Marijke A. M., Sierksma, Annerieke S. R., Rutten, Bart P. F., Dennissen, Frank, Steinbusch, Harry W. M., Lucassen, Paul J., Schmitz, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155024/
https://www.ncbi.nlm.nih.gov/pubmed/21409417
http://dx.doi.org/10.1007/s00429-011-0305-1