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Age-related changes of neuron numbers in the frontal cortex of a transgenic mouse model of Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative disorder, characterized by amyloid plaque accumulation, intracellular tangles and neuronal loss in selective brain regions. The frontal cortex, important for executive functioning, is one of the regions that are affected. Here, we investigated the neur...
Autores principales: | Lemmens, Marijke A. M., Sierksma, Annerieke S. R., Rutten, Bart P. F., Dennissen, Frank, Steinbusch, Harry W. M., Lucassen, Paul J., Schmitz, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155024/ https://www.ncbi.nlm.nih.gov/pubmed/21409417 http://dx.doi.org/10.1007/s00429-011-0305-1 |
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