EAF2 loss enhances angiogenic effects of Von Hippel-Lindau heterozygosity on the murine liver and prostate

Von Hippel-Lindau (VHL) disease results from the inactivation of the VHL gene and is characterized by highly vascular tumors. A consequence of VHL loss is the stabilization of hypoxia-inducible factor (HIF) alpha subunits and increased expression of HIF target genes, which include pro-angiogenic gro...

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Detalles Bibliográficos
Autores principales: Pascal, Laura E., Ai, Junkui, Rigatti, Lora H., Lipton, Anne K., Xiao, Wuhan, Gnarra, James R., Wang, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155049/
https://www.ncbi.nlm.nih.gov/pubmed/21638067
http://dx.doi.org/10.1007/s10456-011-9217-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155049/
https://www.ncbi.nlm.nih.gov/pubmed/21638067
http://dx.doi.org/10.1007/s10456-011-9217-1

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