A Safety Evaluation of DAS181, a Sialidase Fusion Protein, in Rodents

DAS181 is a novel inhaled drug candidate blocking influenza virus (IFV) and parainfluenza virus (PIV) infections through removal of sialic acid receptors from epithelial surface of the respiratory tract. To support clinical development, a 28-day Good Laboratory Practices inhalation toxicology study...

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Detalles Bibliográficos
Autores principales: Larson, Jeffrey L., Kang, Seong-Kwi, Choi, Bo In, Hedlund, Maria, Aschenbrenner, Laura M., Cecil, Beth, Machado, GloriaMay, Nieder, Matthew, Fang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Safety Evaluation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155083/
https://www.ncbi.nlm.nih.gov/pubmed/21572096
http://dx.doi.org/10.1093/toxsci/kfr109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155083/
https://www.ncbi.nlm.nih.gov/pubmed/21572096
http://dx.doi.org/10.1093/toxsci/kfr109

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