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The challenge of developing universal vaccines

Antigenic variability of immunodominant antigens is a common mechanism used by pathogens to escape the immune response. Frequently, the proposed solution is a universal vaccine based on conserved antigens present on all strains of the pathogen. Indeed, a lot of progress has been made in the developm...

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Detalles Bibliográficos
Autor principal: Rappuoli, Rino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155208/
https://www.ncbi.nlm.nih.gov/pubmed/21904572
http://dx.doi.org/10.3410/M3-16