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Id2 expression delineates differential checkpoints in the genetic program of CD8α(+) and CD103(+) dendritic cell lineages

Dendritic cells (DCs) have critical roles in the induction of the adaptive immune response. The transcription factors Id2, Batf3 and Irf-8 are required for many aspects of murine DC differentiation including development of CD8α(+) and CD103(+) DCs. How they regulate DC subset specification is not co...

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Detalles Bibliográficos
Autores principales: Jackson, Jacob T, Hu, Yifang, Liu, Ruijie, Masson, Frederick, D'Amico, Angela, Carotta, Sebastian, Xin, Annie, Camilleri, Mary J, Mount, Adele M, Kallies, Axel, Wu, Li, Smyth, Gordon K, Nutt, Stephen L, Belz, Gabrielle T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155298/
https://www.ncbi.nlm.nih.gov/pubmed/21587207
http://dx.doi.org/10.1038/emboj.2011.163