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The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains

The ATP-dependent chromatin-remodelling enzyme Chd1 is a 168-kDa protein consisting of a double chromodomain, Snf2-related ATPase domain, and a C-terminal DNA-binding domain. Here, we show the DNA-binding domain is required for Saccharomyces cerevisiae Chd1 to bind and remodel nucleosomes. The cryst...

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Detalles Bibliográficos
Autores principales: Ryan, Daniel P, Sundaramoorthy, Ramasubramanian, Martin, David, Singh, Vijender, Owen-Hughes, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155300/
https://www.ncbi.nlm.nih.gov/pubmed/21623345
http://dx.doi.org/10.1038/emboj.2011.166