Cargando…
In vitro and in vivo pre-clinical analysis of a F(ab')(2 )fragment of panitumumab for molecular imaging and therapy of HER1-positive cancers
BACKGROUND: The objective of this study was to characterize the in vitro and in vivo properties of the F(ab')(2 )fragment of panitumumab and to investigate its potential for imaging and radioimmunotherapy. METHODS: The panitumumab F(ab')(2 )was generated by enzymatic pepsin digestion. Afte...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155408/ https://www.ncbi.nlm.nih.gov/pubmed/21845232 http://dx.doi.org/10.1186/2191-219X-1-1 |