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Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis

BACKGROUND: The relapsing-remitting dynamics is a hallmark of autoimmune diseases such as Multiple Sclerosis (MS). Although current understanding of both cellular and molecular mechanisms involved in the pathogenesis of autoimmune diseases is significant, how their activity generates this prototypic...

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Detalles Bibliográficos
Autores principales: Vélez de Mendizábal, Nieves, Carneiro, Jorge, Solé, Ricard V, Goñi, Joaquín, Bragard, Jean, Martinez-Forero, Ivan, Martinez-Pasamar, Sara, Sepulcre, Jorge, Torrealdea, Javier, Bagnato, Francesca, Garcia-Ojalvo, Jordi, Villoslada, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155504/
https://www.ncbi.nlm.nih.gov/pubmed/21762505
http://dx.doi.org/10.1186/1752-0509-5-114