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Inferring a Transcriptional Regulatory Network from Gene Expression Data Using Nonlinear Manifold Embedding

Transcriptional networks consist of multiple regulatory layers corresponding to the activity of global regulators, specialized repressors and activators as well as proteins and enzymes shaping the DNA template. Such intrinsic complexity makes uncovering connections difficult and it calls for corresp...

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Detalles Bibliográficos
Autores principales: Zare, Hossein, Kaveh, Mostafa, Khodursky, Arkady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155518/
https://www.ncbi.nlm.nih.gov/pubmed/21857910
http://dx.doi.org/10.1371/journal.pone.0021969