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In Vitro and Ex Vivo Analysis of CHRNA3 and CHRNA5 Haplotype Expression

Genome-wide association studies implicate variations in CHRNA5 and CHRNA3 as being associated with nicotine addiction (NA). Multiple common haplotypes (“risk”, “mixed” and “protective”) exist in Europeans; however, high linkage disequilibrium between variations in CHRNA5 and CHRNA3 makes assigning c...

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Detalles Bibliográficos
Autores principales: Doyle, Glenn A., Wang, Min-Jung, Chou, Andrew D., Oleynick, John U., Arnold, Steven E., Buono, Russell J., Ferraro, Thomas N., Berrettini, Wade H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155531/
https://www.ncbi.nlm.nih.gov/pubmed/21858091
http://dx.doi.org/10.1371/journal.pone.0023373