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Accelerated Vascular Aging in CuZnSOD-Deficient Mice: Impact on EPC Function and Reparative Neovascularization

OBJECTIVE: Aging is associated with increased oxidative stress levels and impaired neovascularization following ischemia. CuZnSOD has an important role to limit oxidative stress in the vasculature. Here we investigated the role of CuZnSOD for the modulation of ischemia-induced neovascularisation dur...

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Detalles Bibliográficos
Autores principales: Groleau, Jessika, Dussault, Sylvie, Turgeon, Julie, Haddad, Paola, Rivard, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155535/
https://www.ncbi.nlm.nih.gov/pubmed/21858065
http://dx.doi.org/10.1371/journal.pone.0023308