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Systematic Targeted Integration to Study Albumin Gene Control Elements

To study transcriptional regulation by distant enhancers, we devised a system of easilymodified reporter plasmids for integration into single-copy targeting cassettes in clones of HuH7, a human hepatocellular carcinoma. The plasmid constructs tested transcriptional function of a 35-kb region that co...

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Detalles Bibliográficos
Autores principales: Bhattacharyya, Sanchari, Tian, Jianmin, Bouhassira, Eric E., Locker, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155544/
https://www.ncbi.nlm.nih.gov/pubmed/21858039
http://dx.doi.org/10.1371/journal.pone.0023234