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Mast Cells Are Critical for Protection against Peptic Ulcers Induced by the NSAID Piroxicam

Many commonly used non-steroidal anti-inflammatory drugs (NSAIDs) also cause gastrointestinal toxicity, including the development of life-threatening peptic ulcers. We report that mast cell-deficient mice have an extremely high incidence of severe peptic ulceration when exposed to the NSAID piroxica...

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Detalles Bibliográficos
Autores principales: Hampton, Daniel D., Hale, Laura P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155563/
https://www.ncbi.nlm.nih.gov/pubmed/21858200
http://dx.doi.org/10.1371/journal.pone.0023669