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Mast Cells Are Critical for Protection against Peptic Ulcers Induced by the NSAID Piroxicam
Many commonly used non-steroidal anti-inflammatory drugs (NSAIDs) also cause gastrointestinal toxicity, including the development of life-threatening peptic ulcers. We report that mast cell-deficient mice have an extremely high incidence of severe peptic ulceration when exposed to the NSAID piroxica...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155563/ https://www.ncbi.nlm.nih.gov/pubmed/21858200 http://dx.doi.org/10.1371/journal.pone.0023669 |