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Probing the Role of Protein Surface Charge in the Activation of PrfA, the Central Regulator of Listeria monocytogenes Pathogenesis

Listeria monocytogenes is a food-borne intracellular bacterial pathogen capable of causing serious human disease. L. monocytogenes survival within mammalian cells depends upon the synthesis of a number of secreted virulence factors whose expression is regulated by the transcriptional activator PrfA....

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Detalles Bibliográficos
Autores principales: Xayarath, Bobbi, Volz, Karl W., Smart, Jennifer I., Freitag, Nancy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155570/
https://www.ncbi.nlm.nih.gov/pubmed/21858145
http://dx.doi.org/10.1371/journal.pone.0023502