esBAF Facilitates Pluripotency by Conditioning the Genome for LIF/STAT3Signalingand by Regulating Polycomb Function

Signaling by the cytokine LIF and its downstream transcription factor, STAT3, prevents differentiation of pluripotent embryonic stem cells (ESCs) by opposing MAP kinase signaling. This contrasts with most cell types where STAT3signaling induces differentiation. We find that STAT3binding across the p...

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Detalles Bibliográficos
Autores principales: Ho, Lena, Miller, Erik L., Ronan, Jehnna L., Ho, Wenqi, Jothi, Raja, Crabtree, Gerald R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155811/
https://www.ncbi.nlm.nih.gov/pubmed/21785422
http://dx.doi.org/10.1038/ncb2285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155811/
https://www.ncbi.nlm.nih.gov/pubmed/21785422
http://dx.doi.org/10.1038/ncb2285

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