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Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genes

BACKGROUND: The cytoadherence of Plasmodium falciparum is thought to be mediated by variant surface antigens (VSA), encoded by var, rif, stevor and pfmc-2tm genes. The last three families have rarely been studied in the context of cytoadherence. As most VSA genes are unique, the variability among se...

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Detalles Bibliográficos
Autores principales: Claessens, Antoine, Ghumra, Ashfaq, Gupta, Archna P, Mok, Sachel, Bozdech, Zbynek, Rowe, J Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155837/
https://www.ncbi.nlm.nih.gov/pubmed/21718533
http://dx.doi.org/10.1186/1475-2875-10-180