Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria

BACKGROUND: Currently, population pharmacokinetic (PK) studies of anti-malarial drugs are designed primarily by the logistical and ethical constraints of taking blood samples from patients, and the statistical models that are fitted to the data are not formally considered. This could lead to impreci...

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Detalles Bibliográficos
Autores principales: Jamsen, Kris M, Duffull, Stephen B, Tarning, Joel, Lindegardh, Niklas, White, Nicholas J, Simpson, Julie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155838/
https://www.ncbi.nlm.nih.gov/pubmed/21722356
http://dx.doi.org/10.1186/1475-2875-10-181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155838/
https://www.ncbi.nlm.nih.gov/pubmed/21722356
http://dx.doi.org/10.1186/1475-2875-10-181

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