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HIV Protein Sequence Hotspots for Crosstalk with Host Hub Proteins

HIV proteins target host hub proteins for transient binding interactions. The presence of viral proteins in the infected cell results in out-competition of host proteins in their interaction with hub proteins, drastically affecting cell physiology. Functional genomics and interactome datasets can be...

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Detalles Bibliográficos
Autores principales: Sarmady, Mahdi, Dampier, William, Tozeren, Aydin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156123/
https://www.ncbi.nlm.nih.gov/pubmed/21858059
http://dx.doi.org/10.1371/journal.pone.0023293