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Reconstitution of the Costunolide Biosynthetic Pathway in Yeast and Nicotiana benthamiana

The sesquiterpene costunolide has a broad range of biological activities and is the parent compound for many other biologically active sesquiterpenes such as parthenolide. Two enzymes of the pathway leading to costunolide have been previously characterized: germacrene A synthase (GAS) and germacrene...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Majdi, Mohammad, Cankar, Katarina, Goedbloed, Miriam, Charnikhova, Tatsiana, Verstappen, Francel W. A., de Vos, Ric C. H., Beekwilder, Jules, van der Krol, Sander, Bouwmeester, Harro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156125/
https://www.ncbi.nlm.nih.gov/pubmed/21858047
http://dx.doi.org/10.1371/journal.pone.0023255