Vitamin D Receptor Deficiency Enhances Wnt/β-Catenin Signaling and Tumor Burden in Colon Cancer

Aberrant activation of the Wnt/β-catenin pathway is critical for the initiation and progression of most colon cancers. This activation provokes the accumulation of nuclear β-catenin and the induction of its target genes. Apc(min/+) mice are the most commonly used model for colon cancer. They harbor...

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Detalles Bibliográficos
Autores principales: Larriba, María Jesús, Ordóñez-Morán, Paloma, Chicote, Irene, Martín-Fernández, Génesis, Puig, Isabel, Muñoz, Alberto, Pálmer, Héctor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156234/
https://www.ncbi.nlm.nih.gov/pubmed/21858154
http://dx.doi.org/10.1371/journal.pone.0023524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156234/
https://www.ncbi.nlm.nih.gov/pubmed/21858154
http://dx.doi.org/10.1371/journal.pone.0023524

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