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Properties and Crystal Structure of Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8
BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is one of the enzymes involved in homocysteine metabolism. Despite considerable genetic and clinical attention, the reaction mechanism and regulation of this enzyme are not fully understood because of difficult production and poor stability. Wh...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156243/ https://www.ncbi.nlm.nih.gov/pubmed/21858212 http://dx.doi.org/10.1371/journal.pone.0023716 |