A critical role for TCF-1 in T-lineage specification and differentiation

The vertebrate thymus provides an inductive environment for T-cell development. Within the thymus, Notch signals are indispensable for imposing the T-cell fate on multipotential hematopoietic progenitors, but the downstream effectors that impart T-lineage specification and commitment are not well un...

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Detalles Bibliográficos
Autores principales: Weber, Brittany Nicole, Chi, Anthony Wei-Shine, Chavez, Alejandro, Yashiro-Ohtani, Yumi, Yang, Qi, Shestova, Olga, Bhandoola, Avinash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156435/
https://www.ncbi.nlm.nih.gov/pubmed/21814277
http://dx.doi.org/10.1038/nature10279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156435/
https://www.ncbi.nlm.nih.gov/pubmed/21814277
http://dx.doi.org/10.1038/nature10279

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