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Caspase-3, myogenic transcription factors and cell cycle inhibitors are regulated by leukemia inhibitory factor to mediate inhibition of myogenic differentiation

BACKGROUND: Leukemia inhibitory factor (LIF) is known to inhibit myogenic differentiation as well as to inhibit apoptosis and caspase-3 activation in non-differentiating myoblasts. In addition caspase-3 activity is required for myogenic differentiation. Therefore the aim of this study was to further...

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Detalles Bibliográficos
Autores principales: Hunt, Liam C, Upadhyay, Aradhana, Jazayeri, Jalal A, Tudor, Elizabeth M, White, Jason D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156640/
https://www.ncbi.nlm.nih.gov/pubmed/21798094
http://dx.doi.org/10.1186/2044-5040-1-17