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Mutation screening of the RNF8, UBC13 and MMS2 genes in Northern Finnish breast cancer families

BACKGROUND: Currently known susceptibility genes such as BRCA1 and BRCA2 explain less than 25% of familial aggregation of breast cancer, which suggests the involvement of additional susceptibility genes. RNF8, UBC13 and MMS2 are involved in the DNA damage response pathway and play important roles in...

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Detalles Bibliográficos
Autores principales: Vuorela, Mikko, Pylkäs, Katri, Winqvist, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156725/
https://www.ncbi.nlm.nih.gov/pubmed/21774837
http://dx.doi.org/10.1186/1471-2350-12-98