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Mutation screening of the RNF8, UBC13 and MMS2 genes in Northern Finnish breast cancer families
BACKGROUND: Currently known susceptibility genes such as BRCA1 and BRCA2 explain less than 25% of familial aggregation of breast cancer, which suggests the involvement of additional susceptibility genes. RNF8, UBC13 and MMS2 are involved in the DNA damage response pathway and play important roles in...
Autores principales: | Vuorela, Mikko, Pylkäs, Katri, Winqvist, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156725/ https://www.ncbi.nlm.nih.gov/pubmed/21774837 http://dx.doi.org/10.1186/1471-2350-12-98 |
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