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Continuous oral chloroquine as a novel route for Plasmodium prophylaxis and cure in experimental murine models

BACKGROUND: Chloroquine (CQ) is utilized as both cure and prophylaxis to Plasmodium infection. In animal studies, CQ administration to experimental animals is via intraperitoneal (i.p.) injection of a single dose that varies from daily to several times per week. Such daily administration can be dist...

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Detalles Bibliográficos
Autores principales: Lewis, Matthew D, Pfeil, Johannes, Mueller, Ann-Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156757/
https://www.ncbi.nlm.nih.gov/pubmed/21798062
http://dx.doi.org/10.1186/1756-0500-4-262