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The Glycan Shield of HIV Is Predominantly Oligomannose Independently of Production System or Viral Clade

The N-linked oligomannose glycans of HIV gp120 are a target for both microbicide and vaccine design. The extent of cross-clade conservation of HIV oligomannose glycans is therefore a critical consideration for the development of HIV prophylaxes. We measured the oligomannose content of virion-associa...

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Detalles Bibliográficos
Autores principales: Bonomelli, Camille, Doores, Katie J., Dunlop, D. Cameron, Thaney, Victoria, Dwek, Raymond A., Burton, Dennis R., Crispin, Max, Scanlan, Christopher N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156772/
https://www.ncbi.nlm.nih.gov/pubmed/21858152
http://dx.doi.org/10.1371/journal.pone.0023521