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Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head
BACKGROUND: The pathogenesis of osteonecrosis of the femoral head (ONFH) has been implicated in hypofibrinolysis and blood supply interruption. Previous studies have demonstrated that decreased fibrinolytic activity due to elevated plasminogen activator inhibitor-1 (PAI-1) levels correlates with ONF...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156806/ https://www.ncbi.nlm.nih.gov/pubmed/21752301 http://dx.doi.org/10.1186/1471-2474-12-160 |