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Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer

Progenitor cells are thought to be an important cell of origin of human malignancies. However, there has not been any single gene that can define mammary bipotential progenitor cells, and as such it has not been possible to use genetic methods to introduce oncogenic alterations into these cells in v...

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Detalles Bibliográficos
Autores principales: Bu, Wen, Chen, Jiang, Morrison, Gladys D., Huang, Shixia, Creighton, Chad J., Huang, Jian, Chamness, Gary C., Hilsenbeck, Susan G., Roop, Dennis R., Leavitt, Andrew D., Li, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156856/
https://www.ncbi.nlm.nih.gov/pubmed/21532625
http://dx.doi.org/10.1038/onc.2011.147