Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencing

BACKGROUND: To identify potential tumor suppressor genes, genome-wide data from exome and transcriptome sequencing were combined to search for genes with loss of heterozygosity and allele-specific expression. The analysis was conducted on the breast cancer cell line HCC1954, and a lymphoblast cell l...

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Detalles Bibliográficos
Autores principales: Zhao, Qi, Kirkness, Ewen F, Caballero, Otavia L, Galante, Pedro A, Parmigiani, Raphael B, Edsall, Lee, Kuan, Samantha, Ye, Zhen, Levy, Samuel, Vasconcelos, Ana Tereza R, Ren, Bing, de Souza, Sandro J, Camargo, Anamaria A, Simpson, Andrew JG, Strausberg, Robert L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156953/
https://www.ncbi.nlm.nih.gov/pubmed/21108794
http://dx.doi.org/10.1186/gb-2010-11-11-r114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156953/
https://www.ncbi.nlm.nih.gov/pubmed/21108794
http://dx.doi.org/10.1186/gb-2010-11-11-r114

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