Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level

BACKGROUND: Targeted re-sequencing of candidate genes in individuals at the extremes of a quantitative phenotype distribution is a method of choice to gain information on the contribution of rare variants to disease susceptibility. The endocannabinoid system mediates signaling in the brain and perip...

Descripción completa

Detalles Bibliográficos
Autores principales: Harismendy, Olivier, Bansal, Vikas, Bhatia, Gaurav, Nakano, Masakazu, Scott, Michael, Wang, Xiaoyun, Dib, Colette, Turlotte, Edouard, Sipe, Jack C, Murray, Sarah S, Deleuze, Jean Francois, Bafna, Vineet, Topol, Eric J, Frazer, Kelly A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156957/
https://www.ncbi.nlm.nih.gov/pubmed/21118518
http://dx.doi.org/10.1186/gb-2010-11-11-r118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156957/
https://www.ncbi.nlm.nih.gov/pubmed/21118518
http://dx.doi.org/10.1186/gb-2010-11-11-r118

Ejemplares similares