Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level

BACKGROUND: Targeted re-sequencing of candidate genes in individuals at the extremes of a quantitative phenotype distribution is a method of choice to gain information on the contribution of rare variants to disease susceptibility. The endocannabinoid system mediates signaling in the brain and perip...

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Detalles Bibliográficos
Autores principales: Harismendy, Olivier, Bansal, Vikas, Bhatia, Gaurav, Nakano, Masakazu, Scott, Michael, Wang, Xiaoyun, Dib, Colette, Turlotte, Edouard, Sipe, Jack C, Murray, Sarah S, Deleuze, Jean Francois, Bafna, Vineet, Topol, Eric J, Frazer, Kelly A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156957/
https://www.ncbi.nlm.nih.gov/pubmed/21118518
http://dx.doi.org/10.1186/gb-2010-11-11-r118

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